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Itching

A night without scratching can start in your dog’s gut.

Baths, new food, drops from the vet. They all work on the skin. This is about the one place they don’t reach, and what it could mean for his nights.

By Dr. Christine Colamonico, DVM

Last Updated 28, September 2026 

There’s a sound an itchy dog makes at night. The licking. It goes on long enough that you start counting.

You’ve tried to make it go away. A medicated bath. A different bag of food. Drops from the vet that bought you a week, maybe two.

And you can see what it costs him. He used to bring the ball back until you gave up first. Now he lies on the rug working a paw. He won’t settle when you stroke him. He doesn’t sleep, so you don’t either.

Here’s the part nobody tells you. Every one of those solutions lands on the skin.

The skin is where you see the itch.


It may not be where the itch starts.

Why It Keeps Coming Back

You see it on the skin. It can start in the gut.

Skin doesn’t decide much on its own. It shows you what is going on somewhere else.

Almost everything your dog eats goes through the gut first.


A crowd of good bacteria lives down there and does the work. They eat fiber.


Sometimes that crowd runs low. A course of antibiotics can do it. So can stress, age, and one food change after another.


When the crowd runs low, the gut can’t keep up.


In dogs, that often shows on the outside. Paws. Ears. Belly. The base of the tail.


So you wash the skin and the itch comes back, because nothing changed where it started.


Fleas, pollen and food can all set off an itch, and your vet is right to check for those. Keep doing what your vet says. This is the part nobody checks.


And this is what you’re after.

A dog that sleeps through the night.

A dog that finishes the walk.

A dog that lies down next to you and stays down.

A gut short on good bacteria needs 2 things

1

The bacteria themselves

One strain, named on the label, with research behind it in dogs.

2

The fiber they eat.

Bacteria with nothing to feed on don’t stay long enough to matter.

Most products give a dog one or the other. Together they have a name: a synbiotic.

If you already tried an allergy chew

You were closer than you think. Most of them carry a probiotic.

The trouble is the chew around it. Flavors, binders, glycerin and sugar keep it soft on a shelf for months, and live bacteria have a hard time with heat and moisture. Right idea, hard way to carry it.

So two people went and made the plain version

Christine and Jérémy created Jope. Jérémy formulated GB-01 himself, and built it backwards from the way most of these get made.

His mother has cats, so dogs were never the only thing in view. Whatever he made had to work for both.


He had spent years around the same conversation. Parents doing everything right, following every instruction, and getting nowhere.

They picked one strain with real research. They added the fiber it eats. Then they left everything else out.

That’s GB-01®. A powder in a capsule that you twist open over dinner.

THE TURNING POINT

What one capsule a day does

Twist it open over dinner and stir. Nothing to talk your dog into, and the same dose whether he’s 6 pounds or 96.

The bacteria and their fiber go down together, so the bacteria arrive with something to eat and stay long enough to do the work.

QUALITY YOU CAN CHECK YOURSELF

What’s on the label

✓

Enterococcus faecium NCIMB 10415, authorized by the European Food Safety Authority for dogs and cats

✓

FOS and acacia gum, the 2 fibers it feeds on

✓

2 billion live bacteria in every capsule

✓

Third party tested batch by batch, certificate posted on the product page

✓

No meat flavoring, no sugar, no glycerin

PROVEN RESULTS

6 clinical trials on the strain

3 in dogs, 3 in cats. One followed 773 dogs living in a shelter, which is about as hard on a gut as it gets. Those trials looked at digestion and gut bacteria, which is the job it does before anything reaches the skin.

6

Clinical trials on the strain

773

Shelter dogs in 1 trial

2

Prebiotic fibers

1

Capsule a day, any size

Start GB-01® for your dog

90-day satisfaction guarantee

A TYPICAL JOPE STORY

What changes, and in what order

Digestion moves first.

Firmer stools, more predictable, and that is usually what parents notice before anything else.

The skin side is slower.

It changes by degrees, and you are with him every day, which is exactly why it is hard to see.

Note the licking, the ears, the coat and how he slept. Most parents only see the difference looking backwards.

Give it every day for 4 to 8 weeks before you judge it. That is the whole ask.

Digestion moves first.

Firmer stools, more predictable, and that is usually what parents notice before anything else.

The skin side is slower.

It changes by degrees, and you are with him every day, which is exactly why it is hard to see.

Note the licking, the ears, the coat and how he slept. Most parents only see the difference looking backwards.

SWITCH TO GB-01®

What dog parents ask first

You have been working on the part you can see.

The gut is the part you have to go looking for, and it is the easiest one to start.

Give it 4 to 8 weeks and let the nights tell you.

START YOUR DOG ON GB-01®

Use code JOPE10 for an extra 10% off in your order

*For new customers only

THE PRODUCT

Jope Synbiotic GB-01® Gut Balance

★★★★★

5.0 · 30+ reviews

● IN STOCK
✓

Strain proven in a 773 shelter dog study

✓

Supports stool consistency

✓
Supports a healthy microbiome
✓
One inactive ingredient
✓
One capsule a day, any size dog
✓
Dogs and cats, from twelve weeks old
✓
Third party tested

SWITCH TO GB-01®

90-day satisfaction guarantee.

Use code JOPE10 for an extra 10% off in your order

*For new customers only

Customer Reviews

Based on 30 reviews
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J
Jeanine S.
I give this to my cat that had mushy poop and now his poop is sold and firm

I give this to my cat that had mushy poop and now his poop is sold and firm. This really works thanks

A
Alice B.
Incredible gut support for large breeds—my Rhodesian Ridgebacks love it!

I cannot say enough good things about the Jope Synbiotic GB-01 Gut Balance Probiotic. I have two Rhodesian Ridgebacks, Maxx and Lucilla, and keeping their sensitive digestive systems balanced is a top priority for our household. Since putting them both on this synbiotic, it has become an essential part of our daily wellness routine.
What I appreciate most about this supplement is the high-quality, filler-free formula. It combines clinically backed prebiotics and probiotics to truly optimize gut health from the inside out. It comes in convenient powder capsules that are incredibly easy to sprinkle right over their food, and my dogs absolutely love the taste—they devour it without any hesitation!
We have seen such fantastic, consistent results with their digestion that I recently increased our subscription to a bulk six-month supply. Knowing this formula is veterinarian-developed gives me complete peace of mind. I am actively recommending Jope to all of my friends with dogs!

J
Julie D.
Great supplement

I have seen a big difference in my Labrador Retriever who has had GI issues since he was a baby. His poops are firmer and he seems to have less gas and bloating. He has been on this supplement for approximately 4months. We have tried many other brands but this seems to work the best! I would highly recommend 😊

M
Martin H.C.
Noticed a genuine improvement within a week

My youngest dog, Buffy, has always had issues with loose stools and an upset stomach. We had tried different supplements over the years but nothing worked. Within a week we were seeing a massive improvement in her bowel movements and now, after a month, she has almost no bowel issues. I wish I had known about Jope Synbiotic GB-01 sooner. So many years of avoidable butt washes, which she hates more than I do!

The product is super easy to use, just sprinkle and mix it into her dog food. Worth every penny.

M
Martin H.C.
Noticed a genuine improvement within a week

My youngest dog, Buffy, has always had issues with loose stools and an upset stomach. We had tried different supplements over the years but nothing worked. Within a week we were seeing a massive improvement in her bowel movements and now, after a month, she has almost no bowel issues. I wish I had known about Jope Synbiotic GB-01 sooner. So many years of avoidable butt washes, which she hates more than I do!

The product is super easy to use, just sprinkle and mix it into her dog food. Worth every penny.

Try Jope Risk Free

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