Clinically proven formula with E. faecium NCIMB 10415 – 2 Billion CFU
Supports healthy gut and microbiome
Synbiotic power: prebiotic + probiotic
Helps support upset stomach fastfrom $0.75/day
Jope GB-01® subscription plans are unique: after each delivery, an extra 3%, 4%, or 5% discount, depending on your plan, is applied to your previous delivery price, compounding until you reach a total of 50% off.
With each delivery, you pay less until you reach a 50% discount.
Hurry up, this offer might end soon!
Pause or cancel anytime Results in 4-8 weeks
Pause or cancel anytimeResults in 4-8 weeks
Free shipping
90-day satisfaction guarantee
Manufactured in the UK
Order within the next
05h : 12m : 46s
Ships from our US warehouse
Expected delivery in 3-5 days
Order within the next
05h : 12m : 46s
Ships
Active ingredients (per 180 mg capsule):
Other ingredients:
Hydroxypropyl methylcellulose capsule (vegan), magnesium stearate
Orders ship within 24 hours from our US warehouse, except on weekends.
Give one capsule a day. Directly or sprinkled onto your dog's bowl.
Give one capsule a day. Directly or sprinkled onto your cat’s bowl.
Clinically-Proven Formula
1 Capsule For Every Size
90-Day Satisfaction Guarantee
Less Than $1 Per Day
Balance Stools & Digestion
Fewer upset tummies, supported by one of the largest canine probiotic trials
Clinically Validated Probiotic
E. faecium NCIMB 10415, backed by three clinical studies in dogs, and one of the only probiotic strains approved for use in pets by EU regulators
Fast Support
Promotes better daily stools in under 7 days
Synbiotic Power
Associated with FOS + Acacia Gum, which fuels good bacteria and boosts SCFA* production (butyrate & acetate)
Easy To Use
One small capsule a day, whole or sprinkled on food
Clinically Validated Probiotic
E. faecium NCIMB 10415, backed by three clinical studies in cats, and one of the only probiotic strains approved for use in pets by EU regulators
Balance Stools & Digestion
Fewer upset tummies, supported by one of the largest canine probiotic trials
Fast Support
Promotes better daily stools in under 7 days
Synbiotic Power
Associated with FOS + Acacia Gum, which fuels good bacteria and boosts SCFA* production (butyrate & acetate)
Easy To Use
One small capsule a day, whole or sprinkled on food
Whether you need proactive gut support, help with loose stools, or face stressful events like diet changes, travel, or kenneling, GB-01® helps keep your pet’s digestion balanced.
Whether you need proactive gut support, help with loose stools, or face stressful events like diet changes, travel, or kenneling, GB-01® helps keep your pet’s digestion balanced.
From Upset to Balanced
The Gut Shift You’ll Notice
Not All Probiotics Are Equal
Meet The Actives In Synbiotic GB-01®
Enterococcus faecium
NCIMB 10415 / DSM 10663
Enterococcus faecium
NCIMB 10415 / DSM 10663
FOS + Acacia Gum
FOS + Acacia Gum
Not All Probiotics Are Equal
Meet The Actives In Synbiotic GB-01®
Enterococcus faecium
NCIMB 10415 / DSM 10663
Enterococcus faecium
NCIMB 10415 / DSM 10663
FOS + Acacia Gum
FOS + Acacia Gum
100+ Peer-reviewed studies
20+ Probiotic candidates evaluated
Formulated By Veterinarians Who Wanted Better
GB-01® uses E. faecium NCIMB 10415, one of the only probiotic strains validated by the European Food Safety Authority (EFSA) for both safety and efficacy in dogs. EFSA standards are among the strictest in the world. Each batch is third-party tested for strain quantity and purity, so you get exactly what the label promises.
Lab-Verified Ingredient Levels (COA #2503617 – May 2025)
| Ingredient | Verified Amount (per g) | Label Target (per g) | Status | COA Document |
|---|---|---|---|---|
E. faecium NCIMB 10415 |
9.03 × 10¹⁰ CFU |
≥ 1.1 × 10¹⁰ CFU / g |
|
|
Why Synbiotic GB-01®
Stands Apart From Other Probiotics
Jope GB-01®  |
Soft Chew  |
Capsule  | |
|---|---|---|---|
|
Studied Formula |
In 773 shelter dogs |
Pilot study with less than 30 dogs |
No clinical changes |
|
Time To Help Loose Stools |
<7 Days* |
No data |
No data |
|
Clinical Trials In Cats |
3 Studies** |
None |
None |
|
Strain Quality |
EFSA-approved |
Not approved |
Not approved |
|
Inactive Ingredients |
Magnesium stearate only |
Long list |
More inactives |
|
Dose & Convenience |
1 per day |
1 to 3 per day |
1 per day |
|
Subscription Pricing |
Price drops after each delivery, up to 50% discount |
Fixed |
Fixed |
* Based on dog studies conducted with E. faecium NCIMB 10415 alone and the exact combination of GB-01® ingredients.
** Trials conducted with E. faecium NCIMB 10415 showing significant positive results.
The opinions expressed in these testimonials are those of the individual customers and are independent of Jope. They do not constitute an endorsement or a guarantee.
Approved by Thousands of
Furry Friends
GB-01® is a probiotic gut health supplement for dogs and cats. It combines the proven probiotic Enterococcus faecium NCIMB 10415 (DSM 10663) with prebiotics FOS and Acacia gum. This unique blend supports digestive balance, healthy stools, and a strong gut microbiome.
GB-01® is a probiotic gut health supplement for dogs and cats. It combines the proven probiotic Enterococcus faecium NCIMB 10415 (DSM 10663) with prebiotics FOS and Acacia gum. This unique blend supports digestive balance, healthy stools, and a strong gut microbiome.
Yes. It has been demonstrated to be safe for dogs and cats in several studies and confirmed by the European Food Safety Authority (EFSA). GB-01® is safe for long-term daily use in puppies, kittens, adults, seniors, pregnant, and lactating pets. Always check with your veterinarian for your pet’s specific condition.
Clinical studies show that:
Synbiotic GB-01® can be used from 12 weeks of age and older in kittens and puppies. Always consult your veterinarian before starting supplements, especially for very young pets.
Yes. GB-01® is suitable for both cats and dogs of all sizes. The daily dose is one capsule.
The capsule can be:
Yes, with a timing precaution:
No. This gut health probiotic is:
The only inactive ingredient is magnesium stearate. Trace amounts could be present; email us with questions at contact@petjope.com.
We always recommend checking with your veterinarian for your pup’s or cat’s specific condition.
Yes. GB-01® is safe for daily, long-term use. Many pet parents give it every day to maintain gut health. It can also be used short-term—for example, before boarding, during travel, or after antibiotics. For best results, we recommend consistent daily use.
Do not use Synbiotic GB-01® Gut Balance after the Expiration date. The number of live probiotic bacteria (CFU) can no longer be guaranteed.
Yes. GB-01® can be mixed with cooked or raw food. Just make sure the food is cooled to lukewarm or room temperature before adding the probiotic, as heat can kill beneficial bacteria.
Yes. GB-01® is safe for pregnant and lactating pets. In fact, probiotics may support digestive and immune health during these life stages.
GB-01® is safe for long-term, daily use. You can also give it short-term—for example:
It is still safe to use GB-01®. Pet foods may contain probiotics, but often at lower levels or with strains not proven in dogs and cats. GB-01™ provides a clinically validated strain with a guaranteed dose.
Yes. GB-01® is free from yeast, dairy, soy, and wheat. It contains no meat flavoring and no artificial additives, making it a clean and safe probiotic choice.
Please note that there is a possibility of a trace amount of these allergens.
Efficacy of a Probiotic‐Prebiotic Supplement on Incidence of Diarrhea in a Dog Shelter: A Randomized, Double‐Blind, Placebo‐Controlled Trial.
Alterations in Healthy Adult Canine Faecal Microbiome and Selected Metabolites as a Result of Feeding a Commercial Complete Synbiotic Diet with Enterococcus faecium NCIMB 10415.
The Effect of Metronidazole versus a Synbiotic on Clinical Course and Core Intestinal Microbiota in Dogs with Acute Diarrhea.
Opinion on the safety of Oralin® (Enterococcus faecium DSM 10663/NCIMB 10415) for dogs.
Opinion on Oralin® (Enterococcus faecium) for cats (safety and efficacy).
Enterococcus faecium NCIMB 10415 may transiently colonise the canine gastrointestinal tract without affecting the faecal microbiota.
Understanding the canine intestinal microbiota and its modification by pro-, pre- and synbiotics – what is the evidence?
Probiotic mechanisms of action
Probiotics and their validity in small animal patient therapy.
Probiotics in dogs and cats.
Effects of dietary fructooligosaccharide on selected bacterial populations in feces of dogs.
Fructo-oligosaccharide effects on serum cholesterol levels: An overview.
