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Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats
Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats
Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats
Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats
Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats
Synbiotic GB-01 - Gut Balance - 30 count - Probiotic for dogs and cats

Synbiotic GB-01 - Gut Balance - 30 count

Clinically proven probiotic + prebiotic capsule that supports your pet's digestion, microbiome balance, and stool consistency.
Clinically proven formula with <em>E. faecium</em> NCIMB 10415 – 2 Billion CFUClinically proven formula with E. faecium NCIMB 10415 – 2 Billion CFU
Supports healthy gut and microbiomeSupports healthy gut and microbiome
Synbiotic power: prebiotic + probioticSynbiotic power: prebiotic + probiotic
Helps support upset stomach fastHelps support upset stomach fast
Ongoing proactive support leads to stronger results.
$29.90

from $0.75/day

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90-day satisfaction guarantee90-day satisfaction guarantee
Manufactured in the UKManufactured in the UK
Order within the next

Order within the next

05h : 12m : 46s

Ships from our US warehouse

Expected delivery in <strong>3-5 days</strong>

Expected delivery in 3-5 days

Product Facts

Active ingredients (per 180 mg capsule):

  • Enterococcus faecium NCIMB 10415 (DSM 10663): 2 billion CFU
  • Prebiotic Fiber Blend (Fructooligosaccharides + Acacia Gum): 46 mg

Other ingredients:

Hydroxypropyl methylcellulose capsule (vegan), magnesium stearate

Shipping and returns

Orders ship within 24 hours from our US warehouse, except on weekends.

  • Standard shipping is free on all orders
  • Backed by a 90‑day satisfaction guarantee. Vet’s honor: if it’s not the right fit for your dog, we’ll make it right
Directions for Use

Give one capsule a day. Directly or sprinkled onto your dog's bowl.

Directions for Use

Give one capsule a day. Directly or sprinkled onto your cat’s bowl.

Clinically-Proven Formula

Clinically-Proven Formula

1 Capsule For Every Size

1 Capsule For Every Size

90-Day Satisfaction Guarantee

90-Day Satisfaction Guarantee

Less Than $1 Per Day

Less Than $1 Per Day

Transforming Your Dog’s Gut Health Every Day

Balance Stools & Digestion

Balance Stools & Digestion

Fewer upset tummies, supported by one of the largest canine probiotic trials

Clinically Validated Probiotic

Clinically Validated Probiotic

E. faecium NCIMB 10415, backed by three clinical studies in dogs, and one of the only probiotic strains approved for use in pets by EU regulators

Fast Support

Fast Support

Promotes better daily stools in under 7 days

Synbiotic Power

Synbiotic Power

Associated with FOS + Acacia Gum, which fuels good bacteria and boosts SCFA* production (butyrate & acetate)

Easy To Use

Easy To Use

One small capsule a day, whole or sprinkled on food

* SCFA = Short-Chain Fatty Acids
Product image Product image

Transforming Your Cat’s Gut Health Every Day

Clinically Validated Probiotic

Clinically Validated Probiotic

E. faecium NCIMB 10415, backed by three clinical studies in cats, and one of the only probiotic strains approved for use in pets by EU regulators

Balance Stools & Digestion

Balance Stools & Digestion

Fewer upset tummies, supported by one of the largest canine probiotic trials

Fast Support

Fast Support

Promotes better daily stools in under 7 days

Synbiotic Power

Synbiotic Power

Associated with FOS + Acacia Gum, which fuels good bacteria and boosts SCFA* production (butyrate & acetate)

Easy To Use

Easy To Use

One small capsule a day, whole or sprinkled on food

* SCFA = Short-Chain Fatty Acids
Product image Product image

When GB-01® Can Help

Whether you need proactive gut support, help with loose stools, or face stressful events like diet changes, travel, or kenneling, GB-01® helps keep your pet’s digestion balanced.

Food Transitions or Sensitivities
icon
Food Transitions or Sensitivities
Loose Stools
icon
Loose Stools
Proactive Gut Support
icon
Proactive Gut Support
Eating Something They Shouldn’t
icon
Eating Something They Shouldn’t
Stress (Travel, Kenneling, etc.)
icon
Stress (Travel, Kenneling, etc.)

When GB-01® Can Help

Whether you need proactive gut support, help with loose stools, or face stressful events like diet changes, travel, or kenneling, GB-01® helps keep your pet’s digestion balanced.

Food Transitions or Sensitivities
icon
Food Transitions or Sensitivities
Loose Stools
icon
Loose Stools
Proactive Gut Support
icon
Proactive Gut Support
Eating Something They Shouldn’t
icon
Eating Something They Shouldn’t
Stress (Travel, Kenneling, etc.)
icon
Stress (Travel, Kenneling, etc.)

From Upset to Balanced
The Gut Shift You’ll Notice

First Signs
First Few Days
First Signs
You may already notice stools looking more consistent and easier to pick up.
Stomach Comfort
Before 7 Days
Stomach Comfort
Supports a return to normal stool quality and healthy frequency.
Proven Gut Support
After 14 Days
Proven Gut Support
Helps maintain normal stools, balance digestion, and reduce signs of occasional digestive upset.
Lasting Balance
After 30 Days
Lasting Balance
With daily use, GB-01® helps strengthen the gut environment, supporting long-term digestive wellness for your dog or cat.


Not All Probiotics Are Equal
Meet The Actives In Synbiotic GB-01®

Two powerful ingredients. One proven gut solution.

Enterococcus faecium
NCIMB 10415 / DSM 10663

Probiotic clinically proven in 700+ shelter dogs
Supports gut health effectively and helps with stomach upset fast

Enterococcus faecium
NCIMB 10415 / DSM 10663

  • Clinically shown to help with loose stool in less than 7 days
  • Shown to be effective in six different dog and cat clinical trials
The Studies

FOS + Acacia Gum

Prebiotic blend that feeds beneficial bacteria
Produces SCFAs to help support digestion and immune function

FOS + Acacia Gum

  • Shown to increase microbiome diversity in both dogs and cats, helping strengthen resilience against gut upsets
  • Supports natural production of short-chain fatty acids (like butyrate and acetate), which fuel intestinal cells and play a role in immune defense
The Studies

Not All Probiotics Are Equal
Meet The Actives In Synbiotic GB-01®

Two powerful ingredients. One proven gut solution.

Enterococcus faecium
NCIMB 10415 / DSM 10663

Probiotic clinically proven in cats and dogs
Supports gut health effectively and helps with stomach upset fast

Enterococcus faecium
NCIMB 10415 / DSM 10663

  • Clinically shown to help with loose stool in less than 7 days
  • Shown to be effective in six different dog and cat clinical trials
The Studies

FOS + Acacia Gum

Prebiotic blend that feeds beneficial bacteria
Produces SCFAs to help support digestion and immune function

FOS + Acacia Gum

  • Shown to increase microbiome diversity in both dogs and cats, helping strengthen resilience against gut upsets
  • Supports natural production of short-chain fatty acids (like butyrate and acetate), which fuel intestinal cells and play a role in immune defense
The Studies
"We’re practicing veterinarians who saw firsthand how often gut issues affect pets.Seeing so many ineffective products on the market, we dug into the science ourselves. We analyzed clinical studies and strains to find what truly worked for dogs and cats.And we created GB-01®, a supplement we’re proud to recommend and give to our own pets.”
Dr. Jeremy & Dr. Christine, Founders of Jope
<p>Formulated By Veterinarians Who <strong>Wanted Better</strong></p>

100+ Peer-reviewed studies

20+ Probiotic candidates evaluated

Formulated By Veterinarians Who Wanted Better

"We’re practicing veterinarians who saw firsthand how often gut issues affect pets.Seeing so many ineffective products on the market, we dug into the science ourselves. We analyzed clinical studies and strains to find what truly worked for dogs and cats.And we created GB-01®, a supplement we’re proud to recommend and give to our own pets.”
Dr. Jeremy & Dr. Christine, Founders of Jope

GB-01®: Beyond Gut Wellness

Vitality & Energy
Intermittent Itchiness
Skin & Coat Health
Immune Function
Healthy Cholesterol Levels
EFSA-Validated. <strong>Lab-Verified.</strong> Trusted by Vets.

EFSA-Validated. Lab-Verified. Trusted by Vets.

COA Document
EFSA-Validated. <strong>Lab-Verified.</strong> Trusted by Vets.

GB-01® uses E. faecium NCIMB 10415, one of the only probiotic strains validated by the European Food Safety Authority (EFSA) for both safety and efficacy in dogs. EFSA standards are among the strictest in the world. Each batch is third-party tested for strain quantity and purity, so you get exactly what the label promises.

Lab-Verified Ingredient Levels (COA #2503617 – May 2025)

IngredientVerified Amount (per g)Label Target (per g)StatusCOA Document

E. faecium NCIMB 10415

9.03 × 10¹⁰ CFU

≥ 1.1 × 10¹⁰ CFU / g
2 B CFU / 180 mg
guaranteed after 24 mo

EFSA-Validated. <strong>Lab-Verified.</strong> Trusted by Vets.

Why Synbiotic GB-01®
Stands Apart From Other Probiotics

Jope GB-01®

<p>Jope GB-01®</p>

Soft Chew
Best Selling Alt.

<p>Soft Chew <br/>Best Selling Alt.</p>

Capsule
Best Selling Alt.

<p>Capsule <br/>Best Selling Alt.</p>

Studied Formula

In 773 shelter dogs

Pilot study with less than 30 dogs

No clinical changes

Time To Help Loose Stools

<7 Days*

No data

No data

Clinical Trials In Cats

3 Studies**

None

None

Strain Quality

EFSA-approved

Not approved

Not approved

Inactive Ingredients

Magnesium stearate only
Low allergy risk

Long list
High allergy risk

More inactives
High allergy risk

Dose & Convenience

1 per day

1 to 3 per day

1 per day

Subscription Pricing

Price drops after each delivery, up to 50% discount

Fixed

Fixed

* Based on dog studies conducted with E. faecium NCIMB 10415 alone and the exact combination of GB-01® ingredients.
** Trials conducted with E. faecium NCIMB 10415 showing significant positive results.

Commit to Gut Health, Loyalty Pays Off!

  • Better long-term results
    Daily use = lasting results
  • Decreasing price with every order
    3% to 5% less at each delivery
  • Up to 50% off
    You’re rewarded for staying consistent
Loyalty Program Mobile
SUBSCRIBE NOW
Loyalty Program
*Only available by subscription. Up to 50% off list price. Accumulated discount resets if subscription is paused, skipped, or canceled. See Terms of Service for details.
..

Approved by Thousands of
Furry Friends

..
Sarah R. and Jazz
"It did wonders for Jazz’s tummy! His poops look great, and he’s way more energetic and happy!"

Frequently Asked Questions

What is Synbiotic GB-01® Gut Balance (Dog & Cat Probiotic & Prebiotic)?

GB-01® is a probiotic gut health supplement for dogs and cats. It combines the proven probiotic Enterococcus faecium NCIMB 10415 (DSM 10663) with prebiotics FOS and Acacia gum. This unique blend supports digestive balance, healthy stools, and a strong gut microbiome.

What is Synbiotic GB-01® Gut Balance?

GB-01® is a probiotic gut health supplement for dogs and cats. It combines the proven probiotic Enterococcus faecium NCIMB 10415 (DSM 10663) with prebiotics FOS and Acacia gum. This unique blend supports digestive balance, healthy stools, and a strong gut microbiome.

How does this probiotic for dogs and cats work?
  • Probiotic action: E. faecium NCIMB 10415 stabilizes intestinal bacteria and helps with loose stools.

  • Prebiotic support: The FOS + Acacia gum blend feeds beneficial bacteria, helping probiotics colonize the gut.

  • Gut health synergy: Together, they strengthen the gut barrier, regulate immunity, and promote smoother digestion.

Is this probiotic safe for pets?

Yes. It has been demonstrated to be safe for dogs and cats in several studies and confirmed by the European Food Safety Authority (EFSA). GB-01® is safe for long-term daily use in puppies, kittens, adults, seniors, pregnant, and lactating pets. Always check with your veterinarian for your pet’s specific condition.

What benefits can probiotics like GB-01® provide for my dog or cat?

Clinical studies show that:

  • The exact formula of GB-01® supports healthy stool quality in dogs fast

  • E. faecium NCIMB 10415 supports healthy stool quality in cats

  • E. faecium NCIMB 10415 helps protect the microbiome during stress, travel, or diet changes

  • E. faecium NCIMB 10415 maintains healthy bacteria, while antibiotics may disrupt gut balance
At what age can my pet (kitten or puppy) start probiotics?

Synbiotic GB-01® can be used from 12 weeks of age and older in kittens and puppies. Always consult your veterinarian before starting supplements, especially for very young pets.

Can GB-01® probiotics be given to cats?

Yes. GB-01® is suitable for both cats and dogs of all sizes. The daily dose is one capsule.

How do I give this probiotic to my pet?

The capsule can be:

  • Given whole (like a pill)

  • Hidden in a treat

  • Opened and sprinkled onto food (make sure the food is cool, not hot, to keep the probiotics alive).
Can I give this Dog & Cat probiotic + prebiotic alongside antibiotics or medications?

Yes, with a timing precaution:

  • If your pet is on antibiotics, give Synbiotic GB-01® a few hours apart from the antibiotic dose.

  • GB-01® can be safely used with other medications and supplements.
Does Synbiotic GB-01® Gut Balance contain allergens?

No. This gut health probiotic is:

  • Soy-free

  • Wheat-free

  • Dairy-free

  • Yeast-free

  • Free from artificial flavorings

The only inactive ingredient is magnesium stearate. Trace amounts could be present; email us with questions at contact@petjope.com.
We always recommend checking with your veterinarian for your pup’s or cat’s specific condition.

Can I give this probiotic to my pet every day?

Yes. GB-01® is safe for daily, long-term use. Many pet parents give it every day to maintain gut health. It can also be used short-term—for example, before boarding, during travel, or after antibiotics. For best results, we recommend consistent daily use.

How should I store Synbiotic GB-01® probiotics (Dog & Cat Probiotic & Prebiotic)?
  • Store in a cool, dry place, away from direct sunlight.

  • In very hot weather, you may keep it in the refrigerator.

  • Each blister-sealed capsule stays fresh until the printed expiration date.
What happens if the probiotic passes its expiry date?

Do not use Synbiotic GB-01® Gut Balance after the Expiration date. The number of live probiotic bacteria (CFU) can no longer be guaranteed.

Can I use this probiotic with home-cooked or raw food?

Yes. GB-01® can be mixed with cooked or raw food. Just make sure the food is cooled to lukewarm or room temperature before adding the probiotic, as heat can kill beneficial bacteria.

Can GB-01® probiotics be given during pregnancy or lactation?

Yes. GB-01® is safe for pregnant and lactating pets. In fact, probiotics may support digestive and immune health during these life stages.

How long should I give Synbiotic GB-01® probiotics for?

GB-01® is safe for long-term, daily use. You can also give it short-term—for example:

  • A few days before and after boarding, travel, or stressful events

  • During and after an antibiotic course (continue for a few days after finishing antibiotics)
What if my pet already gets probiotics or prebiotics from food?

It is still safe to use GB-01®. Pet foods may contain probiotics, but often at lower levels or with strains not proven in dogs and cats. GB-01™ provides a clinically validated strain with a guaranteed dose.

Is Synbiotic GB-01® yeast-free, dairy-free, and gluten-free?

Yes. GB-01® is free from yeast, dairy, soy, and wheat. It contains no meat flavoring and no artificial additives, making it a clean and safe probiotic choice.

Please note that there is a possibility of a trace amount of these allergens.

Scientific Sources

1
Journal of Veterinary Internal Medicine
2017
Rose, L. et al.

Efficacy of a Probiotic‐Prebiotic Supplement on Incidence of Diarrhea in a Dog Shelter: A Randomized, Double‐Blind, Placebo‐Controlled Trial.

View Study
2
Animals (MDPI)
2022
Nybroe, S. et al.

Alterations in Healthy Adult Canine Faecal Microbiome and Selected Metabolites as a Result of Feeding a Commercial Complete Synbiotic Diet with Enterococcus faecium NCIMB 10415.

View Study
3
Veterinary Sciences
2024
Stübing, H. et al.

The Effect of Metronidazole versus a Synbiotic on Clinical Course and Core Intestinal Microbiota in Dogs with Acute Diarrhea.

View Study
4
EFSA Journal
2024
FEEDAP Panel (EFSA).

Opinion on the safety of Oralin® (Enterococcus faecium DSM 10663/NCIMB 10415) for dogs.

View Study
5
EFSA Journal
2014
FEEDAP Panel (EFSA).

Opinion on Oralin® (Enterococcus faecium) for cats (safety and efficacy).

View Study
6
Royal Veterinary College Poster
2018
Matthewman, L. et al.

Enterococcus faecium NCIMB 10415 may transiently colonise the canine gastrointestinal tract without affecting the faecal microbiota.

View Study
7
Veterinary Medicine and Science
2016
Schmitz, S.; Suchodolski, J.

Understanding the canine intestinal microbiota and its modification by pro-, pre- and synbiotics – what is the evidence?

View Study
8
PubMed Review
2012
Bermudez-Brito, M. et al.

Probiotic mechanisms of action

View Study
9
Vet Times
2015
Chandler, M.

Probiotics and their validity in small animal patient therapy.

View Study
10
Vet Times
2015
Chandler, M.

Probiotics in dogs and cats.

View Study
11
American Journal of Veterinary Research
2000
Willard, M. D. et al.

Effects of dietary fructooligosaccharide on selected bacterial populations in feces of dogs.

View Study
12
British Journal of Nutrition
2015
Costa, G. T. et al.

Fructo-oligosaccharide effects on serum cholesterol levels: An overview.

View Study
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