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| 242 Reviews

| 242 Reviews

|  242 Reviews

Finally, A Joint Supplement Worth Prescribing!

Join the hundreds of vets who are switching from glucosamine to Jope.

They Trust Us

Made By Vets, For Vets

Jope is founded and owned by two passionate and independent vets, Dr. Christine and Dr. Jeremy.

They are dedicated to partnering with other veterinarians to further improve the health of our four-legged companions.

Unlock The Potential Of
UC-II® Collagen

We selected our active ingredients after reviewing over 85 studies (and counting!):

  • UC-II® collagen, which has repeatedly shown benefits for dog joint health in scientific studies
  • EPA & DHA in higher doses than leading soft chew brands
  • Curcumin from turmeric with 95% concentrated extracts

Four Reasons to Choose Jope

Glucosamine Is No Longer The Gold Standard

Objective Studies Outcomes
Results on GFP (Ground Force Plate)
Jope’s Active Ingredients

Positive for UC-II® collagen(1), EPA and DHA(2) (Ground Force Plate)

UC-II®: +42% on impulse area
            +20% on peak vertical force(1)

Omega-3: Change in PVF of 3.5 BW VS 0.5 BW for CTR(2)

Glucosamine-based Supplements

Glucosamine and chondroitin have failed to demonstrate efficacy(1) (3)

Not Significant(1) (4) (5)  

Comparative Studies

UC-II® collagen > Glucosamine and chondroitin(1)(6)

Official AAHA 2022 Guidelines
Healthy Dog Efficacy Studies

EPA and DHA are tier 1 recommendations (7)
for Joint health

Suggested benefits in two studies conducted on healthy Labradors under an intense exercise regimen: a healthy inflammatory response and cartilage production. (8) (9)

Glucosamine is not quoted as recommended in the conclusion (7)

None  

References

  1. Gupta, R C et al. : “Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate.” Journal of animal physiology and animal nutrition vol. 96,5 (2012): 770-7.
  2. Gruen, Margaret E et al. : “Effects of feeding a high omega-3 fatty acids diet in dogs with naturally occurring osteoarthritis.” Journal of animal physiology and animal nutrition vol. 97,5 (2013): 830-7.
  3. Scott, Ruth M et al. : “Efficacy of an oral nutraceutical for the treatment of canine osteoarthritis. A double-blind, randomized, placebo- controlled prospective clinical trial.” Veterinary and comparative orthopaedics and traumatology : V.C.O.T vol. 30,5 (2017): 318-323.
  4. Kampa, Naruepon et al. : “Study of the effectiveness of glucosamine and chondroitin sulfate, marine based fatty acid compounds (PCSO-524 and EAB-277), and carprofen for the treatment of dogs with hip osteoarthritis: A prospective, block-randomized, doubleblinded, placebo-controlled clinical trial.” Frontiers in veterinary science vol. 10 1033188. 1 Feb. 2023.
  5. Moreau, M et al. : “Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis.” The Veterinary record vol. 152,11 (2003): 323-9.
  6. D’Altilio, M et al. : “Therapeutic Efficacy and Safety of Undenatured Type II Collagen Singly or in Combination with Glucosamine and Chondroitin in Arthritic Dogs.” Toxicology mechanisms and methods vol. 17,4 (2007): 189-96.
  7. Gruen, Margaret E et al. : “2022 AAHA Pain Management Guidelines for Dogs and Cats.” Journal of the American Animal Hospital Association vol. 58,2 (2022): 55-76.
  8. Varney, Jessica L et al. : “Undenatured type II collagen mitigates inflammation and cartilage degeneration in healthy Labrador Retrievers during an exercise regimen.” Translational animal science vol. 5,2 txab084. 10 May. 2021.
  9. Varney, Jessica L et al. : “Impact of supplemented undenatured type II collagen on pain and mobility in healthy Labrador Retrievers during an exercise regimen.” Translational animal science vol. 6,3 txac123. 27 Aug. 2022.

Published Reviews

2020 Review

2020 Review

« UC-II administration has been reported to be more effective than the most frequently used glucosamine and chondroitin sulfate supplements in joint health studies that were done with humans and animals. » (10)

2017 Glucosamine Review

« Although glucosamine and chondroitin have benign adverse effect profiles, the clinical benefit of using these agents remains questionable. » (11)

 

 

2022 Nutraceutical Review(12)

EPA & DHA: « For omega-3-based compounds, ie, categories 1 and 2 the results of all previous reviews support our inferences with a high level of comfort that these products are highly effective. »

UC-II® collagen: « lt, therefore, appears impossible to rule, at the present time, on an indication for collagen in canine OA based on the results of this meta-analysis. »

NB: In this review, they didn't separate UC-II® collagen from other collagen supplements. They also couldn't include four clinical studies that came out in 2022 or after.

Glucosamine: « The systematic review of the literature included nine trials that evaluated, mostly in combination, glucosamine hydrochloride and chondroitin sulphate. Chondroitin-glucosamine nutraceuticals (ctg. 4) showed strong evidence of non-effect and a significant statistical difference in efficacy from the other categories (ctg. 1, 2, 3 and 5) in the meta-analysis ».

 

 

References

  1. Gencoglu, Hasan et al. “Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals.” Animals : an open access journal from MDPI vol. 10,4 697. 17 Apr. 2020..
  1. Bhathal, Angel et al. “Glucosamine and chondroitin use in canines for osteoarthritis: A review.” Open veterinary journal vol. 7,1 (2017): 36-49.
  1. Barbeau-Grégoire, Maude et al. “A 2022 Systematic Review and Meta-Analysis of Enriched Therapeutic Diets and Nutraceuticals in Canine and Feline Osteoarthritis.” International journal of molecular sciences vol. 23,18 10384. 8 Sep. 2022

Pet Parents And Vets Love it!

Our clients love it so far, none of our clients had anything negative to say about Jope. I had inserted one of the real reviews from a client below
“I love it because he thinks they are treats and he liked the way they taste and he walked better and not in pain so they work very well for him.”
Allied Animal Healthcare

Science Meets Exceptional Quality

Each batch is third-party tested for active ingredient quantities

Small batch produced in The Midwest

Made in a GMP-compliant, SQF-certified, and NASC-approved facility

It's An Evidence Based Supplement

UC-II® collagen, a patented, undenatured type II collagen, uniquely modulates the immune response to support healthy joints. It supports normal inflammatory pathways and cartilage production, resulting in comprehensive joint health.

Numerous clinical studies have shown UC-II® to be significantly more effective than traditional ingredients like glucosamine and chondroitin.

For veterinarians, UC-II® collagen presents a scientifically backed and naturally occurring solution to enhance joint health in pets, making it an essential addition to your practice.

Are You Ready To Learn More ?

With the kind authorization of the Gramercy Animal Hospital team.

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