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I'm a veterinarian. I said glucosamine doesn't work, and a lawyer's letter arrived.

Here are the 85 studies that got me into trouble and what parents saw when they switched

By Christine Colamonico, veterinarian and co-founder of Jope

4 min read.

They say a joint chew is all your dog needs.
They say it on the bag.
They say it in the ads.

But what none of them will ever say is what's in most of those chews.

Glucosamine.

And what independent studies found about it.
I said it.
That's how I ended up holding this letter.
If your dog takes a joint chew, you should see those studies too.

It started with my dog, Pepsi

Pepsi had joint problems.
So I did what most people would do. I gave him glucosamine. For months. I saw no results.

I tried other things too. Some didn't work. Some made him feel bad.

And the strange part is, I shouldn't have been surprised.
Back in vet school, even my professors said glucosamine didn't really work.

There was just nothing better at the time.
So it kept getting recommended anyway.
So I dove into the science.

Here are the studies

I reviewed more than 85 studies in dogs. A lot of them said the same thing. Glucosamine didn't work for a lot of dogs.

You don't have to take my word for it. Here's what a recent, independent review of nutraceuticals concluded.

"Chondroitin-glucosamine nutraceuticals showed strong evidence of non-effect (…) the results of the present meta-analysis led to the conclusion that chondroitin-glucosamine nutraceuticals should not be prescribed in canine or feline arthritis."

Barbeau-Grégoire et al., International Journal of Molecular Sciences, 2022. OA: osteoarthritis.

“

And here's a review from before that.

"Although glucosamine and chondroitin have benign adverse effect profiles, the clinical benefit of using these agents remains questionable."

Bhathal et al., Open Veterinary Journal, 2017.

“
And it went beyond studies

This next part happened years later.
But it belongs here.

A major glucosamine joint supplement maker agreed to an $11.5 million class action settlement over advertising claims about its dog joint supplements.

Plaintiffs alleged those claims were not supported by clinical evidence.
The company denied wrongdoing, and settled.
As part of the agreement, it agreed to remove specific joint and mobility claims from its packaging.

What worked for Pepsi

Back to Pepsi.
In those same 85 studies, I found something else.
A molecule called UC-II® collagen.
It has more than 10 studies in dogs.

And when it was tested head to head against glucosamine plus chondroitin, it was 59% more effective.

59%

It also works in a different way.

Glucosamine

Glucosamine is meant to be a building block for the joint.

UC-II®

UC-II® goes through the gut instead.
It is recognized there.
And it teaches the body to recognize its own cartilage as its own, and not attack it.

I combined it with 2 other proven ingredients.

Omega 3

High dose Omega 3, the EPA and DHA from anchovy oil.

curcumin

And concentrated curcumin from turmeric.

I gave them to Pepsi.
And I finally had something that worked for him.

So Jeremy and I made Jope

That's when I realized this couldn't only be for my dog.
A lot of pup parents were struggling like I was.

So my co-founder Jeremy and I created Jope.
We're both veterinarians.
We formulated it ourselves. No marketing team.

There's no glucosamine in it.
We left it out on purpose.

It’s made in the Midwest, USA.
SQF certified, GMP, NASC.
And every single batch is third-party tested.

MADE IN USA

SQF · GMP 

THIRD-PARTY TESTED EVERY BATCH

LIMITED-INGREDIENT, MOSTLY ORGANIC

Then the letter came

I started sharing what I'd found.
Blog articles with my cofounder.
Podcasts. Articles for other veterinarians.

I've been critical of glucosamine. But I always backed it up with independent studies. Was I wrong to do that?

One day, the letter came.
My heart sank.
I thought it was the end.
A big company was threatening to sue us for defamation.
To shut us down.
Why?
We were growing. We were making noise.
Pup parents were finally seeing what the studies say.
And that was bad for their business.
But everything we shared came from studies.
You just read two of them.
So we didn't back down.
We're still sharing them.

If you want to try what worked for Pepsi

Here's what I can tell you.

Jope has UC-II®, high dose Omega 3 and concentrated curcumin.
It has no glucosamine.

And it comes with a 90-day money back guarantee.
If you give it to your dog and see no change, you get your money back.

You know your dog better than anyone.
If nothing has changed on what you're giving now,
this is the one I made.
A bag of Jope Hip & Joint Dog Chews surrounded by ingredients like turmeric root and omega-3 capsules.
Jope Hip & Joint Dog Chews
✓

No glucosamine, by design

✓
UC-II®, high dose Omega 3, concentrated curcumin
✓
Veterinarian founded and veterinarian formulated
✓
Made in the USA, third party tested every batch
✓

90-day money back guarantee

Get Jope Hip & Joint
We even have a special offer to get you started.

Customer Reviews

Based on 1266 reviews
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j
judy s.
She’s gone, but I remeber!

Hi jope!
Perhaps you’re wondering why, with Kika gone, I still stay signed up to the jope newsletter?
We, here’s the thing - jope contributed so much to her quality of life and health that I WANT to be reminded of how great this product is. I gave away dozens of bags left from our jope stash when she passed. I recommend it to everyone I know or meet with a senior dog. I tell the story of how I forgot to order it one week and the difference was instantly see-able. How I never missed an order again. I will always be greatful for discovering jope. And when I finally heal enough to think about a new dog - jope will be on my list. So yeh, don’t unsubscribe me please. Sharing this. As always.

P
PETINA

Noticed a difference in our elderly dogs agility within a week.

R
Rosa

So far so good my lab has improved in walking up the stairs

B
Brian

Helps my dog like I never woulda believed

D
David S.
Franklin is back to jumping on the couch

Franklin is a very active 6-1/2 year old dog. He spends most of his day running. About a year ago, he started limping and stopped jumping on the couch. We gave him glucosamine supplements. They helped his limping, but he still didn't jump on the couch. After switching to Jope, he's back on the couch.

That may not be a good thing for our sofa, but it's good to get our couch cuddling time back.

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