My 13 year old 70 lb dog is now in his 4th month of Jope

My 13 year old 70 lb dog is now in his 4th month of Jope. He recently suffered an injury to his left hind leg, which left him with apparent neurological injury, which you can still pick up on in the video but it has improved so much. I feel like Jope had a part in his recovery, but did not notice much until the end of the 3rd month. He had a TPLO on the left hind and torn CCL on his right but it was not repaired. I see a big difference in the ease with which he can get up now and hope to see continued improvement as he continues with the Jope.

Seriously surprised at the difference in my dog

I've got a rescue pitty mix that has had a bad lump in his left front leg since I got him 3 years ago. In that time I've tried several different joint supplements. Giving each one at least 3 months to show signs of improvement. Nothing has worked. I ordered Jope after seeing an ad, and by the second month saw a bit of improvement. We are now on month 4 and I kid you not, he has improved to a degree I didn't think possible. We go on longer walks and the other day when he saw a squirrel in the yard, he took off in a full sprint after it. I had never seen him run before that. He did not limp at all afterwards either.
Consider us both huge fans of Jope. Best joint supplement I've tried in 30+ years of dog ownership.

I was skeptical reading all of the positive reviews but…

I was skeptical reading all of the positive reviews but, after two months we kind of have a different dog. Our 11-year-old Australian Cattle Dog was a life-long athlete keeping up on trail runs and mountain bike rides but some of that extremism had him declining rapidly. We aren't certain if it is 100% Jope or also being much more active and swimming all summer but he is doing things with ease now (like running upstairs or jumping into the car) that took great effort just two months ago. Everyone says he is looking fit again too. It's kind of magical.

So Easy and he LOVES them!

So Easy and he LOVES them! We rescued Benny (bullmastiff) at around 1 yr old, and knew quickly we needed to add in a quality supplement. We've sadly had many surgeries on our other mastiffs and will do whatever possible to keep Benny healthy as long as possible.

Puppy Energy Again

My dog has had joint issues and our vet recommended starting jope and within months the difference was noticeable. He has had more energy and less pain and he is back to his old puppy energy.

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Why Your Vet Still Recommends Glucosamine (And What Your Dog Actually Needs Instead)

by Dr. Jeremy A.-B., DVM

March 12, 2026

Every joint supplement for dogs has the same star ingredient: Glucosamine + Chondroitin.

And for millions of dogs — maybe yours — it's been a recurring disappointment.

You've seen it. You've probably tried it. You've watched your dog continue to struggle anyway.

But what if the problem isn't your dog?

What if the industry has been recommending an outdated solution?

In 2022, the American Animal Hospital Association (AAHA) — the body that sets the standard of care for vets — did something significant in their official canine guidelines for joint health.

They completely removed glucosamine.

Its highest recommendation (Tier 1) in terms of supplements now goes to Omega-3s.

And newer ingredients, such as UC-II® collagen, are expected to be integrated into future recommendations.

These specific ingredients are clinically shown to support a healthy inflammatory response and help dogs move comfortably again.

But if the "Bible of Veterinary Medicine" changed the rules, why is the old standard still everywhere?

For the industry, it's simple: glucosamine is cheap and familiar.

For your primary care vet, it's about time.

They are experts at general health, but they often don't have the luxury of deep-diving into the latest clinical shifts in orthopedic journals.

However, specialists who focus exclusively on complex joint cases have already made the switch.

They have moved to UC-II® collagen and Omega-3s because the evidence is compelling.

For your dog, that translates to a real chance to run, jump, and play with confidence again.

Is it only because of the AAHA recommendations?

No. The evidence supporting UC-II® collagen has grown significantly over the past five years, with more than 10 studies now demonstrating its efficacy.

This is just an excerpt from a 2020 review that analyzed multiple studies made on UC-II® collagen.

If you want to explore further, do your own research. Go to https://pubmed.ncbi.nlm.nih.gov/ and search for “UC-II® for dogs.”

And if you would like to read more about why glucosamine is not recommended anymore, you can find this review on the same website: https://pubmed.ncbi.nlm.nih.gov/2833 1832/.

What Makes UC-II® Collagen Different?

If your dog hesitates before jumping or struggles to stand up, here's what's actually happening:

Cartilage wears down. Tiny fragments end up in the joint fluid.

Your dog's immune system sees them as "foreign invaders" and attacks - creating a vicious cycle of discomfort.

Glucosamine tries (and only tries) to rebuild cartilage while this attack is happening.

It's like trying to renovate a house while the fire is still burning.

UC-II® focuses on the fire.

It uses a mechanism called "oral tolerance."

When your dog swallows UC-II®, it helps "retrain" the immune system to recognize Type II collagen as safe.

Once the "attack" is managed, your dog's joints can finally maintain their own cartilage and recover.

TRY UC-II® Supplement

The Research Backs This Up

In head-to-head clinical trials, dogs on glucosamine often showed very low to no objective improvement.¹

That's the difference between your dog hesitating at the stairs and bounding up them with confidence again.

In this 5-month study, UC-II® collagen was shown to be 59% more effective than glucosamine.

Another head-to-head comparison between UC-II® and glucosamine used Ground Force Plate technology, which objectively measures how much weight a dog can comfortably place on their paws. The results showed:

UC-II® collagen (40 mg): +42% improvement in mobility (impulse area)

Glucosamine (2000 mg) + chondroitin (1600 mg): no significant results

Why Some UC-II® Products Still Don't Work

Here is the problem: Just because a label says "contains UC-II®" doesn't mean it will deliver results.

In fact, many standard joint chews get four critical things wrong:

Bad Formula Some brands mix UC-II® with glucosamine. This is a massive mistake. It has been shown in a study that this combination is less effective than UC-II® collagen alone.

Wrong Form UC-II® must be undenatured - meaning it hasn't been heat-processed. Cheap manufacturing destroys its biological activity.²

Missing Synergy UC-II® helps the immune system to act on the joint, but without high-dose Omega-3s to support a healthy inflammatory response, and Curcumin for the antioxidant effect, the recovery is only half-complete.⁵⁻¹²

Wrong Dose Clinical studies prove 40 mg is the effective dose for medium-sized dogs. Most products underdose to save money.³

Jope: Built to a Specialist's Protocol

When Dr. Chrisine’s dog Pepsi was struggling, we read 85 clinical trials until we found the answer.

We formulated Jope to match the exact protocol that helped Pepsi go from having a hard time standing to enjoying his active life again.

We have a Certificate of Analysis for every batch to ensure the doses are exact and third-party validated:

But clinical precision doesn't matter if your dog won't eat it.

That's why we spent months perfecting a soft-chew that dogs actually treat like a reward, not a pill.

Daily Routine:

Dogs under 25 lbs: 1 chew

Dogs 25-75 lbs: 2 chews

Dogs over 75 lbs: 3 chews

No fighting. Just an easy daily routine your dog will look forward to.

Try Jope Risk-Free

Studies are important. Real results are even more.

Most Jope customers had already tried several supplements before. Some were recommended glucosamine. Others were simply looking for a cheaper option.

And many of them say the same thing in their reviews:

"I tried everything and nothing worked until I found Jope."

The reviews you see below come from people who tried other solutions, who were skeptical about supplements, and who sometimes believed there was no real solution left.

We are proud that we could help them and their pups during those difficult moments, when other products had failed.

And we will be even more proud the day pup parents consider Jope with UC-II® as their first solution, not their last one.

What to Expect

Weeks 3–4

The "retraining" of the body begins. Many owners notice more energy and a greater willingness to play.

Note: Do not worry if you do not see this after four weeks. The best results often appear later.

Weeks 6–8

More confidence in daily movements. Playing with toys or climbing stairs with less visible stiffness and getting up with less hesitation.

Weeks 10–12

The full benefits of the protocol are visible. Dogs move with the ease of their younger selves.

Important: This isn't a "quick fix". It's a biological retraining. It takes time, but because you're supporting the root of the issue, the results are sustainable.

Try It Risk-Free for 90 Days

We give your dog a full 90 days to experience this formula.

If your dog doesn't start moving easier, jumping on the couch without hesitation, or running to greet you at the door, we don't want your money. No questions asked.

Your dog was there when you needed them most.

When the house felt too quiet, or you came home exhausted. They never asked for anything in return.

Now, as their mobility slows, it's your turn to be there for them.

20,000+ dog parents every month have already made the switch.

Their dogs are moving better. Yours could be next.

Give Your Dog Their Mobility Back — 90-Day Guarantee →

You still have questions? We are here for you!

Scientific References

¹ Gupta, R. C. et al. (2012). Comparative therapeutic efficacy and safety of type-II collagen (UC-II®), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. Journal of Animal Physiology and Animal Nutrition, 96(5), 770-777.

² Gencoglu, H. et al. (2020). Undenatured Type II Collagen (UC-II®) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals. Animals, 10(4), 697.

³ D'Altilio, M. et al. (2007). Therapeutic Efficacy and Safety of Undenatured Type II Collagen Singly or in Combination with Glucosamine and Chondroitin in Arthritic Dogs. Journal of Veterinary Pharmacology and Therapeutics, 30(Suppl 1), 1-8.

⁵⁻⁹ Roush, J. K. et al. (2010). Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. Journal of the American Veterinary Medical Association, 236(1), 67-73.

¹²⁻¹⁴ Peng, Y. et al. (2021). Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures. Drug Design, Development and Therapy, 15, 4503-4525.

Disclaimer:

Jope is a dietary supplement for companion animals and is not a substitute for a balanced diet. Follow the recommendations on petjope.com and the dosages advised. If your pet is on medication or suffers from a medical condition, consult a veterinarian. If your pet shows unusual symptoms while using Jope, contact customer care. If symptoms persist or you are in doubt, stop using the product and consult your veterinarian. This article is an advertorial written by veterinarians at Jope.

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